Livealth Biopharma Private Limited

Artesunate suppositories are used for the treatment of malaria. Artesunate is an antimalarial water-soluble derivative of dihydroartemisinin.

Main Use of Artesunate Suppositories

✅ Severe Malaria (Plasmodium falciparum)

Purpose: Rapidly reduce malaria parasite load in the blood to prevent death or complications.

Formulation: Rectal suppository – inserted into the rectum for absorption when a patient cannot take oral medicine or there is no access to IV treatment.

Ideal for:

Children under 6 years

Unconscious or vomiting patients

Remote areas where transport to a hospital takes several hours or more

Antimalarial medications, also known as antimalarials, are designed to prevent or cure malaria. Such drugs may be used for some or all of the following:

Treatment of malaria in individuals with suspected or confirmed infection

Prevention of infection in individuals visiting a malaria-endemic region who have no immunity (Malaria prophylaxis)

Routine intermittent treatment of certain groups in endemic regions (Intermittent preventive therapy)

Some antimalarial agents, particularly chloroquine and hydroxychloroquine, are also used in the treatment of rheumatoid arthritis and lupus-associated arthritis.

• Malaria
• Prevent night cramps in adults and the elderly when sleep is regularly disrupted.

Artesunate is developed for killing the erythrocytic stage of plasmodium asexual form. It is effective to malaria caused by chloroquine resistant stain of plasmodium falciparum. It can quickly and reliably control the acute attack of malaria. It is suitable to salvage the patients with pernicious malaria and treat P. falciparum malaria and P. vivax malaria. Artesunate Injection is indicated for the treatment of serious malaria infections and the patients with cerebral malaria.

The combination of artemether and lumefantrine is used to treat certain kinds of malaria infections (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death). Artemether and lumefantrine should not be used to prevent malaria. Artemether and lumefantrine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.

Mefloquine
This   medication   is   used   to   treat   and prevent    malaria.

• Malaria
• And prevent night cramps in adults and the elderly when sleep is regularly disrupted.

Quinine Dihydrochloride Inj 300 Mg/ml For the treatment of acute attacks of malaria, including attacks due to chloroquine resistant or multi drug resistant strains of Plasmodium falciparum.

Specifications:

Quinine is used parenterally for cerebral, severe or complicated malaria, or when vomiting prevents retention of an orally administered drug.Quinine dihydrochloride is the salt usually employed for the preparation of injections.Quinine acts primarily as a schizonticide i.e. it suppresses the asexual cycle of development of malaria parasites in the erythrocytes. It has little effect on sporozoites or pre erythrocytic forms of malarial parasites. It does not, therefore, prevent the relapse of Plasmodium vivax infections.

Quinine is also gametocidal for P. vivax and P. malariae but not for Plasmodium falciparum, and therefore does not prevent transmission of this infection by the mosquito.

Plasma concentrations of quinine between 8 and 15 mg/litre are effective clinically and are generally non-toxic; such values are usually achieved with the standard therapeutic dose.

Approximately 70% of quinine is bound to proteins in the plasma in healthy subjects, rising to about 90% in patients with malaria.

Used to Treat: Malaria and prevent night cramps in adults and the elderly when sleep is regularly disrupted.

Chloroquine Phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. Chloroquine Phosphate Tablets are an antimalarial and amebicidal drug.

The combination of artemether and lumefantrine is used to treat certain kinds of malaria infections (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death). Artemether and lumefantrine should not be used to prevent malaria. Artemether and lumefantrine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.